2016.05.17

Prof. Toshi Sunazuka was an invited speaker at "the 25th French- Japanese Symposium on Medicinal and Fine Chemistry (FJS 2016)" that was held on May 15-18th, 2016 at Keio Plaza Hotel Tama, Tokyo, Japan.
Title; > In the Harmony between Natural Products and Organic Synthesis

2016.05.07

Update Publications page.Toshiaki Sunazuka "Professor Amos B Smith, III"
J. Antibiot. 2016, 69, 190.

2016.04.12

Update Publications page.
Takeshi Yamada, Koh Suzuki, Tomoyasu Hirose, Takumi Furuta, Yoshihiro Ueda, Takeo Kawabata, Satoshi Ōmura and Toshiaki Sunazuka
"Organocatalytic Site-Selective Acylation of Avermectin B2a, a Unique Endectocidal Drug"
Chem. Pharm. Bull, 2016, 64, 856-864.

2016.04.11

Hirokazu Takada (D2) and Goh Sennari (D2) were awarded oral presentation award in "The 136th Annual Meeting of the Pharmaceutical Society of Japan" that was held in March 26-29, 2016 at pacifico YOKOHAMA, Kanagawa, Japan.
Congratulations!
Title;  Progress Towards the Total Synthesis of Mangromicins, Potent anti-Trypanosomal Activity
Title;  Divergent synthesis and structure-activity relationships of Puberulic acids, potent antimalarial agents

2016.03.14

Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura appeared on TV program.
Data: March 13, 2016 (9:00 am~)
Program: "Nichiyo-Bijutsukan" (Japan Broadcasting Corporation)
http://www.nhk.or.jp/nichibi/index.html
This TV program will be rerun on March 20.

2016.03.09

58th KMC Frontier Seminar was held.
Date; March 9, 2015 at Kitasato University, Tokyo, Japan
Speaker; Prof. E. Peter. KÜNDIG (University of GENEVA)
Title; ASYMMETRIC PD-NHC* CATALYZED C(sp3)-H BOND FUNCTIONALIZATION

2016.03.03

Update Publications page.
Masanori Yanagi, Ryo Ninomiya, Yoshihiro Ueda, Takumi Furuta, Takeshi Yamada, Toshiaki Sunazuka and Takeo Kawabata
"Organocatalytic Site-Selective Acylation of 10-Deacetylbaccatin III"
Chem. Pharm. Bull, 2016, 64, 907-912.

2016.03.01

Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura has been featured in the magazine "MOKU, March, 2016" that was published by MOKU publishing Co.
(Published on March 1st, 2016)
【特集】誰もやらないことをやる！

2016.02.16

59th KMC Frontier Seminar was held.
Date; March 25, 2015 at Kitasato University, Tokyo, Japan
Speaker; Prof. Barry M. Trost (Stanford University)
Title;  SELF-ASSEMBLY OF DINUCLEAR MAIN GROUP COMPLEXES FOR ASYMMETRIC CATALYSIS

58th KMC Frontier Seminar was held.
Date; March 9, 2015 at Kitasato University, Tokyo, Japan
Speaker; Prof. E. Peter. KÜNDIG (University of GENEVA)
Title; ASYMMETRIC PD-NHC* CATALYZED C(sp3)-H BOND FUNCTIONALIZATION

The book about Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura "大村智博士の一期一会　次代へつなぐ30の言葉" was published by The Yamanashi NICHINICHI Shinbun (Feb 10, 2016).

2016.01.30

Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura appeared on TV program.
Data: January 30, 2016 (7:30 am~)
Program: "Sawako-no Asa" (MBS Television)
http://www.mbs.jp/sawako/

2016.01.11

Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura has been featured in the magazine "AERA '16.01.11" that was published by ASAHI.
【大村 智…ビル・ゲイツを生み出したい】

2016.01.05

Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura has been featured in the magazine that was published by TAKARAJIMASHA on January 5th, 2016.
『大村智と梶田隆章 ノーベル賞受賞者という生き方』

2016.01.04

A Happy New Year!

2015.12.22

The research meeting of The Kitasato Institute for Life Sciences in 2015 was held.

2015.12.21

Prof. Toshi Sunazuka was an invited speaker at "Pacifichem 2015" that was held on December 15-20, 2015 at Honolulu, Hawaii, US.
Title; > Drug discovery based on microbial bioactive natural products
Title; > Isolation and total synthesis of microbial natural products

2015.12.20

Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura has been featured in the jorunal "化学と生物" that was published by Japan society for bioscience biotechnology and agrochemistry on December 20th, 2015.
『化学と生物』Vol.54 (2016) No.1

2015.12.18

Update Publications page.
Shohei Toguchi, Tomoyasu Hirose, Kazuko Yorita, Kiyoshi Fukui, K. Barry Sharpless, Satoshi Ōmura, Toshiaki Sunazuka
"In situ Click Chemistry for the Identification of a Potent D-Amino Acid Oxidase Inhibitor"
Chem. Pharm. Bull, 2016, 64, 695-703.

2015.12.16

Ph.D thesis seminer was held. 
We had three presentation on this time.

2015.12.11

The Nobel Prize Award Ceremony took place at the Stockholm Concert Hall, Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura was awarded "the Nobel Prize in Physiology or Medicine 2015".
Congratulations!
Learn more (click here)

2015.12.09

Assistant professor Takeshi Yamada was awarded "Eisai Award 2015" in Synthetic Organic Chemistry, Japan
Congratulations!
Research project:  カスケード反応を駆使した特異な大環状炭素環天然物の全合成とアフリカ睡眠病治療薬の創製研究

2015.12.08

Update Publications page
Jun Oshita, Yoshihiko Noguchi, Akito Watanabe, Goh Sennari, Shogo Sato, Tomoyasu Hirose, Daiki Oikawa, Yuki Inahashi, Masato Iwatsuki, Aki Ishiyama, Satoshi Ōmura and Toshiaki Sunazuka
"Towards the total synthesis of the anti-trypanosomal macrolide, Actinoallolides; construction of a key linear intermediate"
Tetrahedron Lett. 2015, In Press.
Doi: 10.1016/j.tetlet.2015.12.022

2015.12.08

Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura delivered his Nobel Lecture on 7 December 2015 at Aula Medica, Karolinska Institutet in Stockholm.
Title; > A splendid gift from the Earth: The origins & impact of Avermectin
Learn more (click here)

2015.12.07

The book about Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura "> 大村智ものがたり　苦しい道こそ楽しい人生" that was written by Mr. Rensei BABA will be published (Dec 10, 2015).
http://mainichibooks.com/books/nonfiction/post-133.html

2015.12.04

The e-book about Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura "> 至誠天に通ず" has been published by Jitsugyo no Nihon Sha, Ltd. (Dec 04, 2015).

2015.12.01

The memorial special poster
" 人類を疾病から救う微生物の役割"
under the supervision of Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura has been published.

2015.11.30

The book about Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura "大村 智物語ーノーベル賞への歩み" that was written by Mr. Rensei BABA has been just published (Nov 27, 2015).
http://www.chuko.co.jp/tanko/2015/11/004808.html

2015.11.29

Prof. Yoko Takahashi was appeared on the TV program "Science ZERO" broadcasted by Nippon Hoso Kyokai (Japan Broadcasting Corporation).
Data: November 29, 2015
Title; 祝！ノーベル賞（１）大村智さん 微生物から薬を生み出せ！
Program: "Science ZERO" (NHK Television)

2015.11.21

Prof. Toshi Sunazuka was an invited speaker at "Niigata (Nagaoka) Symposium" that was held on November 21-22, 2015 at National Institute, Nagaoka College, Niigata, Japan.
Title; 特異な多環式含窒素生物活性天然物の分子骨格構築法の開発と全合成

2015.11.20

Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura has been featured in the magazine "Bijutsu-no-mado" that was published by Seikatsu no Tomo Co.
(Published on November 20th)
【> 祝！ノーベル賞 50人が語る大村智】

2015.11.16

The following paper of our lab has been selected as a "Most Accessed in 10/2015" in Chem. Eur. J.
" Asymmetric Total Synthesis of Indole Alkaloids Containing An Indoline Spiroaminal Framework."
Chem. Eur. J. 2015, 21, 11855-11864.

2015.11.13

Update Publications page
Shuntaro Mukai, Shota Moriya, Masaki Hiramoto, Hiromi Kazama, Hiroko Kokuba, Xiao-Fang Che, Tomohisa Yokoyama, Satoshi Sakamoto, Akihiro Sugawara, Toshiaki Sunazuka, Satoshi Ōmura, Hiroshi Handa, Takao Itoi and Keisuke Miyazawa
"Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines"
Int. j. clin. oncol. 2015, Just Accepted.

2015.10.30

Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura was awarded "Order of Culture in 2015" from Government of Japan.
Congratulations!

2015.10.19

Prof. Toshi Sunazuka was an invited speaker at "Symposium in Honor of Professor Amos B. Smith, III; The Recipient of the 2015 Allan R. Day Award" that was held on October 17, 2015 at University of Pennsylvania, Philadelphia, US.

2015.10.07

Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura appeared on TV program.
Data: October 7, 2015 (7:30 pm~)
Program: "Close-up Gendai" (NHK Television)
http://www.nhk.or.jp/gendai/

2015.10.07

Graduate school entrance examination of three bachelor students was finished.

2015.10.06

Prof. Toshi Sunazuka appeared on TV program.
Data: October 6, 2015 (3:50 pm~)
Program: "Minna no News" (Fuji Television)
http://www.fujitv.co.jp/en/news_programming.html

2015.10.05

Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura and two scientists have won "The Nobel Prize in Physiology or Medicine 2015"
Congratulations!
http://www.nobelprize.org/nobel_prizes/medicine/laureates/2015/

2015.09.26

Shohei Toguchi (D3, oral), Hirokazu Takada (D2, poster) and Goh Sennari (D2, poster) were awarded oral & poster presentation award in "All Kitasato Project Study, The 9th Kitasato Chemistry Symposium" that was held in September 26, 2015 at Kitasato University, Tokyo, Japan.
Congratulations!
Title; > In situ click chemistryを利用したD-アミノ酸酸化酵素阻害剤の探索研究
Title;  特異な三環性骨格を有するマングロマイシン類の全合成研究
Title;  抗マラリア活性を有するPuberulic acidの多様性指向型合成と構造活性相関研究

2015.09.26

11-members of our lab gave oral and poster presentation in "All Kitasato Project Study, The 9th Kitasato Chemistry Symposium" that was held in September 26, 2015 at Kitasato University, Tokyo, Japan.

2015.09.17

The 32nd Seminar on Synthetic Oeganic Chemistry was held from September 15th to 17th, 2015 at Yugawara, Japan.

2015.09.15

Akito Watanabe (M1) was awarded oral presentation award in "59th The Pharmaceutical Society of Japan" that was held in September 12nd, 2015 at Chiba, Japan.
Congratulations!
Title; > 抗トリパノソーマ活性を有するActinoallolide Aの全合成研究

2015.09.14

56th KMC Frontier Seminar was held.
Date; July 12, 2015 at Kitasato University, Tokyo, Japan
Speaker; Prof. Sarah E. Reisman (California Institute of Technology)
Title;  NECESSITY IS THE MOTHER OF INVENTION:  NATURAL PRODUCTS AND THE CHEMISTRY THEY INSPIRE

2015.09.11

Ph.D candidate Aoi Kimishima (D3) gave an oral presentation at 57th Symposium on the Chemistry of Natural Products that was held from September 9-11, 2015 at Kanagawa Kenmin Hall, Kanagawa, Japan.
Title; > Toward total synthesis of Luminamicin, A potent anti-anaerobic bacterial agent.

2015.09.09

Prof. Toshi Sunazuka was an invited speaker at The 6th Japanese-Sino Symposium on Organic Chemistry for Young Scientists that was held from September 6-9, 2015 at Akiu Resort Hotel Crescent, Miyagi, Japan.
Title; > Syntheses of Biologically Active Natural Products by Means of Cascade Reactions

2015.09.07

Update Publications page
Nadine Lusamba Kalonji, Kazuhiro Nomura, Tetsuaki Kawase, Chiharu Ota, Hiroshi Kubo, Takeya Sato, Teruyuki Yanagisawa, Toshiaki Sunazuka, Satoshi Ōmura and Mutsuo Yamaha
"The non-antibiotic macrolide EM900 inhibits rhinovirus infection and cytokine production in human airway epithelial cells"
Physiological Reports 2015, Just Accepted.

2015.08.19

Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura has been hilighted in the feature article of Grobal Health at Website (Yahoo! JAPAN).
[Learn More below]
http://ghitfund.yahoo.co.jp/

2015.08.13

Assistant prof. Takeshi Yamada was awarded Certificate of Outstanding Contribution in Reviewing Bioorganic & Medicinal Chemistry Letters (Elsevier). You are awarded this status as you are in the top 10th percentile in terms of the number of reviews completed for Recognized Reviewer in the past two years.

2015.08.13

Update Publications page

Sugawara A.; Shima H.; Sueki A.; Hirose T.; Matsui H.; Hanaki H.; Akagawa KS.; Ōmura S. and Sunazuka T.
12-Membered non-antibiotic macrolides EM900 series; Design, synthesis, biological evaluation, and effect in cigarette-smoking model."
J. Antibiot. 2015, Doi: 10.1038/ja.2015.91.

2015.07.31

English page has opend!

2015.07.20

The book "人生に美を添えて" that was written by Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura has been published by Seikatsu no Tomo Co.
(Jul 20, 2015).
https://www.tomosha.com/webshop/products/SOOMURA

2015.07.10

Prof. Toshi Sunazuka is an invited speaker at the 70th Memorial Symposium of The Society of Synthetic Organic Chemistry, Japan, Kanto Branch (Niigata (Nagaoka) symposium) to be held from November 21-22, 2015 at Nagaoka National College of Technology, Niigata, Japan.

2015.07.07

Prof. Toshi Sunazuka was an invited speaker at the Lecture of Chemical Society of Japan, Kanto Branch, Gunma area held in July 7, 2015 at Gunma University, Gunma, Japan.
Title: > 天然有機化合物の魅力を引き出す有機合成化学の醍醐味

2015.06.18

Prof. Toshi Sunazuka was an invited speaker at 16th Tetrahedron Symposium that was held in June 16-19, 2015 at Grand Hyatt Berlin, Germany.
Title:  Total synthesis of unique polycyclic bioactive indole alkaloids

2015.06.13

Update Research > Completed synthetic projects page

2015.06.05

The 4th Tishler-Ōmura Symposium to be held in July 12, 2015 at Kitasato University, Tokyo, Japan.

2015.06.05

Update Publications page

Takeshi Yamada, Tetsuya Ideguchi-Matsushita, Tomoyasu Hirose, Tatsuya Shirahata, Rei Hokari, Aki Ishiyama, Masato Iwatsuki, Akihiro Sugawara, Yoshinori Kobayashi, Kazuhiko Otoguro, Satoshi Ōmura and Toshiaki Sunazuka
"Asymmetric Total Synthesis of Indole Alkaloids Containing An Indoline Spiroaminal Framework."
Chem. E. J. 2015, 21, 11855-11864.
 
Akihiro Sugawara, Nobuo Maita, Hiroaki Gouda, Tsuyoshi Yamamoto, Tomoyasu Hirose, Saori Kimura, Yoshifumi Saito, Hayato Nakano, Takako Kasai, Hirofumi Nakano, Kazuro Shiomi, Shuichi Hirono, Takeshi Watanabe, Hisaaki Taniguchi, Satoshi Ōmura and Toshiaki Sunazuka
"Creation of customised bioactivity within a 14-membered macrolide scaffold: design, synthesis, and biological evaluation using a family-18 chitinase."
J. Med. Chem. 2015 ASAP,
DOI: 10.1021/acs.jmedchem.5b00175

2015.04.06

The special lecture by Distinguished Emeritus Professor and Special Coordinator, Satoshi Ōmura at Toyohashi University of Technology has been featured on the book " 創造の源流 2015年版 社会を変えるイノベーション".
(Apr 6, 2015)

2015.04.01

Ph.D Candidate Goh Sennari was awarded a JSPS Fellowship (DC1).

2015.04.01

Our laboratory invited Dr. Yoshihiko Noguchi as a new assistant professer.

2015.04.01

The Sunazuka group in 2015/2016 has started with new members.